Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging
Source: NCBI BioProject (ID PRJNA187178)
Source: NCBI BioProject (ID PRJNA187178)
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Project name: Mus musculus
Description: Gene Expression profiling of HSCs isolated at different stages of ontogeny to address correlation between gene expression and changes in DNA methylationOverall design: Gene expression profiling of hematopoietic stem cells isolated from e14.5 fetal liver (lineage- ckit+ sca1+CD150+ CD48- Mac1+), 3 month old mice (lineage- ckit+ sca1+ CD34- Flk2-) and 25 month old mice (lineage- ckit+ sca1+ CD34- Flk2-)
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Boston Childrens Hospital
Literatures
- PMID: 23415915
Last updated: 2013-01-24