Thymidine Kinase and mtDNA Depletion in Human Cardiomyopathy: Epigentic and Translational Evidence for Energy Starvation
Source: NCBI BioProject (ID PRJNA186556)
Source: NCBI BioProject (ID PRJNA186556)
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Project name: Homo sapiens
Description: A comparison of epigenetic nuclear DNA methylation and gene expression changes between human dialated cardiomypathy left ventricle samples and non-failing cardiac left ventricule samplesThis study addresses how depletion of huaman cardiac left ventricle mitochondrial DNA and epigentic nuclear DNA methylation promote cardiac dysfunction in human dilated cardiomyopathy.Overall design: Each sample was fluorescently labeled and hybridized to Roche Nimblegen 2.1M Deluxe Promoter Arrays and Expression arrays.
Data type: Other
Sample scope: Multiisolate
Relevance: Medical
Organization: Lewis Lab, Pathology, Emory University
Last updated: 2013-01-10