Comparison of gene expression profile of naive versus arsenic trioxide resistant acute promyelocytic leukemia cell line NB4
Source: NCBI BioProject (ID PRJNA178950)
Source: NCBI BioProject (ID PRJNA178950)
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Project name: Homo sapiens
Description: The aim of this study was to gain insight into the potential mechanism of resistance to arsenic trioxide (ATO). The gene expression profile of naive (NB4) (Acute promyelocytic leukemia (APL) cell line and one of its in house generated ATO resistant sub clone (NB4-VM-AsR1) was done using whole genome microarray and compared to generate the differential expression profile which will give insight into the mechanisms of ATO resistance in APL.Overall design: Agilent one-color experiment,Organism: Human ,Agilent Whole Genome Human 4x44k (AMADID: 014850) , Labeling kit: Agilent Quick-Amp labeling Kit (p/n5190-0442)naive versus arsenic trioxide resistant acute promyelocytic leukemia cell line NB4
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Medical
Organization: Genotypic Technology
Literatures
- PMID: 25822503
Last updated: 2012-11-05