Effect of PRR15 knockdown on human trophoblast cell gene expression
Source: NCBI BioProject (ID PRJNA177068)
Source: NCBI BioProject (ID PRJNA177068)
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Project name: Homo sapiens
Description: Proline rich 15 (PRR15) is a small nuclear protein required for normal conceptus development in the sheep.We used microarrays to assess the changes in the trophoblast transcriptome when PRR15 expression was diminished.Overall design: The human first-trimester trophoblast cell line, ACH-3P, was infected with control lentivirus expressing no shRNA or lentivirus expressing shRNA to target PRR15 mRNA for degradation, with three biological replicates per treatment.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Medical
Organization: Biomedical Sciences, Colorado State University
Last updated: 2012-10-10