Robust 4C-seq data analysis to screen for regulatory DNA interactions
Source: NCBI BioProject (ID PRJNA173815)
Source: NCBI BioProject (ID PRJNA173815)
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Project name: Mus musculus
Description: Regulatory DNA elements can control expression of distant genes via physical interactions. Here, we present a cost-effective methodology and computational analysis pipeline for robust characterization of the physical organization around selected promoters and other functional elements using Chromosome Conformation Capture combined with high-throughput sequencing (4C-Seq) data. Our approach can be multiplexed and routinely integrated with other functional genomics assays to facilitate physical characterization of gene regulation.
Data type: other
Sample scope: Monoisolate
Relevance: Other
Organization: Weizmann Institute of Science
Last updated: 2012-08-27