Regulation of gene expressions in vivo by anti-VEGF and anti-Notch therapy [Mouse430_2]
Source: NCBI BioProject (ID PRJNA170839)
Source: NCBI BioProject (ID PRJNA170839)
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Project name: Homo sapiens
Description: U87-EV human glioblastoma xenograft tumours is therapeutically treated by bevacizumab, a humanized anti-human VEGF mAb, or dibenzazepine (DBZ) when tumour is established in BALB/c SCID mice. At the end point, collect tumour samples and extracted total RNA for microarray to investigate the gene profile changes compared to control. These include the genes from human tumour cells and mouse host stroma cells.Overall design: 5 control, 5 dibenzazepine-treated, and 4 bevacizumab-treated samples
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Medical
Organization: University of Oxford
Literatures
- PMID: 23871637
Last updated: 2012-07-17