Project name: Mus musculus

Description: Robust identification of placental PPARg target genes via mutliple PPARg-dependence criteria.Integration of differential expression data from Pparg-null, Rxra-null, Med1-nul and Ncoa6-null placentas and from WT and Pparg-null Trophoblast stem cells (TSC) differentiated for 2 or 4 days in the presence or absence of the PPARg agonist Rosiglitazone (Rosi).Overall design: [Placentas]Three pools of three WT placentas, each vs a litter-matched pool of three Pparg-null placentasThree pools of three WT placentas, each vs a litter-matched pool of three Rxra-null placentasThree pools of three WT placentas, each vs a litter-matched pool of three Med1-null placentasThree pools of three WT placentas, each vs a litter-matched pool of three Ncoa6-null placentas[Trophoblast stem cells (TSC)]Three independent WT TSC lines differentiated for two and four days in the presence or absence of Rosi vs two independent Pparg-null TSC lines differntiated for the same durations in the presence of Rosi

Data type: Transcriptome or Gene expression

Sample scope: Multiisolate

Relevance: ModelOrganism

Last updated: 2012-07-10