Project name: Homo sapiens

Description: We report the application of methylated DNA immunoprecipitation followed by next-generation sequencing to trisomy 8 AML. Through a global study and quantifying the methylation signals, we demonstrated a characteristic DNA methylation distribution for trisomy 8 indicating the impact of the hypermethylation of the extrachromosome 8 on suppressing the signals on the rest of the chromosomes.Overall design: Examination of 3 relapse trisomy 8 AML patients

Data type: Epigenomics

Sample scope: Multiisolate

Relevance: Medical

Last updated: 2012-06-05