miR-155 promotes Th17 development by targeting Jarid2
Source: NCBI BioProject (ID PRJNA158955)
Source: NCBI BioProject (ID PRJNA158955)
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Project name: Mus musculus
Description: Genome-wide analysis was performed on microRNA 155+/+ and -/- Th17 cells to determine the differentially expressed transcripts that are regulated by miR-155. We found that Jarid2 was differentially expressed in absence of miR-155 and highlight the mechanism for the silencing of IL-22 by Jarid2 and PRC2 in miR-155-/- Th17 cells.Overall design: Comparison of transcriptome of Th17 cells in presence or absence of microRNA 155
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Department of Neuroscience, University of Texas Southwestern Medical Center
Literatures
- PMID: 24856900
Last updated: 2012-04-12