Genome wide DNA methylation analysis of leukemia and reprogrammed leukemia cells (sequencing)
Source: NCBI BioProject (ID PRJNA156619)
Source: NCBI BioProject (ID PRJNA156619)
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Project name: Homo sapiens
Description: We analyzed the methylation pattern of a well characterized leukemia cell line, named K562. Furthermore, we decided to investigate how the malignant epiegenome change during the reprogramming processOverall design: We used RRBS analysis to investigate the methylation pattern in leukemia and reprogrammed leukemia (LiPS).We show that the erasure of the epigenetic aberrancies have functional consequences on leukemia phenotype
Data type: Epigenomics
Sample scope: Multiisolate
Relevance: Medical
Organization: Faculty of Medicine, Discipline of Genetics, Memorial University of Newfoundland
Last updated: 2011-10-25