Synergistic effects of TRAIL and taurolidine on soft tissue sarcoma cell lines
Source: NCBI BioProject (ID PRJNA153731)
Source: NCBI BioProject (ID PRJNA153731)
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Project name: Homo sapiens
Description: Microarray analysis revealed differential gene expression patterns of rhabdomyosarcoma (A-204), leiomyosarcoma (SK-LMS-1) and epithelioid cell sarcoma (VA-ES-BJ) cells treated with TRAIL and/or taurolidine.To explore new therapeutic options in the treatment of sarcomas, we tested the antibiotic taurolidine (TRD) on A-204, SK-LMS-1 and VA-ES-BJ carcinoma cell lines alone and in combination with rhTRAIL (TNF related apoptosis-inducing ligand). Gene expression was analysed by RNA microarray.Overall design: Cell lines were treated with Taurolidine, Trail and a combination of both and compaired to untreated cells
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Medical
Organization: BioChip Lab, Universitaetsklinikum, Institut fuer Zellbiologie
Last updated: 2012-03-16