Microarray analysis to identify genes that are differentially expressed in resting and in LPS-activated splenic B cells of Ebf1+/fl-RERTCre and Ebf1fl/fl-RERTCre mice
Source: NCBI BioProject (ID PRJNA151811)
Source: NCBI BioProject (ID PRJNA151811)
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Project name: Mus musculus
Description: Using resting and LPS-stimulated B cells from mice carrying two Ebf1 alleles flanked with loxP sites and an inducible Cre recombinase, target genes of Ebf 1 and the effect of Ebf1 deletion on the cells was analyzed.Target genes of Ebf 1 and the effect of Ebf1 deletion on the cells was analyzed.Overall design: Ebf1 fl/fl mice and heterozygote control animals carrying an ER-Cre fusion protein were treated with Tamoxifen-Citrate and were sacrificed for analysis. Resting B cells were sorted and were either left untreated or were stimulated with LPS, followed by RNA extraction for expression analysis.See related Series GSE35915.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Grosschedl lab, Cellular & Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics
Literatures
- PMID: 22431510
Release date: 2012-04-03
Last updated: 2012-02-24