Role and function of Bcor in BCR-ABL1 driven pre-B cells
Source: NCBI BioProject (ID PRJNA150219)
Source: NCBI BioProject (ID PRJNA150219)
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Project name: Mus musculus
Description: In order to investigate the function of Bcor in ALL, we isolated bone marrow cells from Bcor fl/Y mice and transformed them with BCR-ABL1. In a second transduction the BCR-ABL1 driven pre-B cells were transformed either with CRE-ERT2 or ERT2 (PMIP) and after 2 days of treatment with 4OH-Tamoxifen (0.5 micromolar) subjected to gene expression analysis.Overall design: Two days after treatment with 4OH-Tamoxifen (0.5 micromolar) total RNA of Puromycin resistant cells was extracted and subjected to gene expression analysis.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Müschen Lab, Childrens Hospital Los Angeles, University of Southern California
Last updated: 2012-01-03