The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells
Source: NCBI BioProject (ID PRJNA149801)

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Project name: Homo sapiens
Description: Array-CGH experiments of HER2+ breast cancer cell lines grown under standard conditions.Overall design: All hybridizations performed using pooled normal female DNA as reference. 11 cell lines profiled in total, 10 HER2+, 1 HER2-. Each was hybridized once on an Agilent 244k aCGH microarray.
Data type: Variation
Sample scope: Multiisolate
Relevance: Medical
Organization: Institute for Molecular Medicine, University of Helsinki
Literatures
  1. PMID: 23253899
Last updated: 2011-12-07