Innate immune agonist, dsRNA, induces apoptosis in ovarian cancer cells and enhances the potency of cytotoxic chemotherapeutics
Source: NCBI BioProject (ID PRJNA148971)
Source: NCBI BioProject (ID PRJNA148971)
0 0
Project name: Homo sapiens
Description: This study aimed at characterizing the effect of the innate immune agonist, dsRNA, on ovarian cancer cell lines and ascites-derived ovarian cancer cells.DsRNA stimulation revealed two sub-populations of ovarian cancer cells, dsRNA sensitive and dsRNA resistant, that could be categorized based upon dsRNA-induced dsRNA receptor expression.Overall design: Human ovarian cancer cell lines were treated with pI:pC and compared against untreated cells.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Medical
Organization: VCU
Release date: 2012-04-29
Last updated: 2011-10-31