Integrated epigenome profiling of repressive histone modifications, DNA methylation and gene expression in normal and malignant urothelial cells [ChIP-Seq data]
Source: NCBI BioProject (ID PRJNA144937)
Source: NCBI BioProject (ID PRJNA144937)
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Project name: Homo sapiens
Description: We profiled two repressive histone modifications (H3K9m3 and H3K27m3) using ChIP-Seq in normal urothelial cells and cell lines representing non-invasive and invasive tumors.Overall design: Two bladder cancer cell lines (RT112 and EJ/T24 from ATCC) and normal human urothelial (NHU) cells were treated according to standard ChIP-Seq protocols using antibodies against the histone modifications H3K9m3 and H3K27m3 (from Millipore). The sequencing reads were mapped against the human genome (GRCh37/hg19).
Data type: Epigenomics
Sample scope: Multiisolate
Relevance: Medical
Organization: MNI, Technische Hochschule MIttelhessen
Literatures
- PMID: 22412920
Release date: 2011-08-03
Last updated: 2011-08-02