Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells (gene expression)
Source: NCBI BioProject (ID PRJNA144309)
Source: NCBI BioProject (ID PRJNA144309)
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Project name: Homo sapiens
Description: We report that hyperglycemia-mediated induction of genes and pathways associated to endothelial dysfunction occur through modulation of acetylated H3K9/K14 inversely correlated with methyl-CpG content.Overall design: Examination of H3K9/K14 histone acetylation and DNA methylation in hyperglycemic conditions.see GSE29251 for histone acetylation and DNA methylation
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Medical
Organization: Human Epigenetics, Diabetes, Monash University Central Clinical School
Literatures
- PMID: 21890681
Release date: 2011-07-20
Last updated: 2011-07-19