Human Fetal and Adult Peripheral Naïve CD4+ T cells and CD4+CD25+ Treg cells
Source: NCBI BioProject (ID PRJNA142745)
Source: NCBI BioProject (ID PRJNA142745)
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Project name: Homo sapiens
Description: We compared differences in fetal and adult T cells by performing whole genome profiling on sort-purified T cells (naïve CD4+ and Treg cells) from human fetal specimens (18-22 gestational weeks) and adult specimens (age 25-40 years old). Fetal and Adult Naïve CD4+ T cells phenotype: CD3+CD4+CD45RA+CCR7+CD27+, Fetal and Adult CD4+CD25+ Treg phenotype: CD3+CD4+CD25brightOverall design: Four different groups were analyzed: Fetal Naïve CD4+ T cells, Adult Naïve CD4+ T cells, Fetal Treg cells, Adult Treg cells. For each group three independent donors were analyzed.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Medical
Organization: Joseph M. McCune lab, Division of Experimental Medicine, University of California San Francisco
Literatures
- PMID: 21164017
Last updated: 2010-11-02