Expression Profiling of Pancreatic Xenografts and Cell Lines
Source: NCBI BioProject (ID PRJNA142407)
Source: NCBI BioProject (ID PRJNA142407)
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Project name: Homo sapiens
Description: Expression profiling of 70 Pancreatic Ductal Adenocarcinoma (PDAC) samples was performed on Agilent 44K expression arrays for cancer gene discovery. Additionally, matched aCGH on Agilent 244K arrays was performed. These two datasets were integrated in order to identify driver mutations leading to pancreatic cancer. Promising candidates were interrogated further using functional studies.Overall design: 68 tumor samples (48 xenografts, 20 cell lines). 2 color arrays hybridized against a common reference pool of RNA from 11 cancer cell lines
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Medical
Organization: Boris Bastian, Pathology and Dermatology, University of California San Francisco
Literatures
- PMID: 22233809
Last updated: 2010-12-15