Chromosome wide analysis of parental allele specific chromatin and DNA methylation along the central part of mouse chr7
Source: NCBI BioProject (ID PRJNA141995)
Source: NCBI BioProject (ID PRJNA141995)
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Project name: Mus musculus
Description: Imprinted genes are monoallelically expressed according to parental inheritance. The maternally and paternally inherited alleles are distinguished epigenetically by DNA methylation and histone modifications.Chromosome-wide Chromatin immunoprecipitation (ChIP) and MIRA analysis of MatDup.dist7 and PatDup.dist7 MEFs provided a panoramic map of reciprocal allele-specific histone modifications and DNA methylation at imprinted genes along distal chromosome 7 and 15.Overall design: ChIP-chip and MIRA-chip was done to map histone modifications and DNA methylation along central chr7 in the maternal allele and paternal allele in Matdup.dist7 and Patdup.dist7 MEFs, respectively, using Nimblegen tiling arrays for central chr7.
Data type: Epigenomics
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Biomedical Informatics, City of Hope National Medical Center
Literatures
- PMID: 21321082
Release date: 2011-03-31
Last updated: 2011-01-26