Integrative genomic analysis of sporadic clear cell Renal Cell Carcinoma
Source: NCBI BioProject (ID PRJNA137871)
Source: NCBI BioProject (ID PRJNA137871)
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Project name: Homo sapiens
Description: Human clear cell renal cell carcinoma (ccRCC) is a common cancer of the kidney. We applied an integrated approach to identify important factors that influence carcinogenesis in ccRCC.Overall design: 33 frozen ccRCC samples were subject to copy number analysis. The data was analyzed to identify factors affecting tumorigenesis. The samples were also stained for HIF-1alpha and HIF-2alpha expression. The tumors were subtyped based on HIF expression and investigated for differences in genetic aberrations.
Data type: Variation
Sample scope: Multiisolate
Relevance: Medical
Organization: University of Pennsylvania School of Medicine
Literatures
- PMID: 22094876
Release date: 2011-12-01
Last updated: 2011-03-09