Gene expression data from liver of rat fed a high-fat diet and high-fructose water without/with Eucommia ulmoides leaves
Source: NCBI BioProject (ID PRJNA132859)
Source: NCBI BioProject (ID PRJNA132859)
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Project name: Rattus norvegicus
Description: To investigate effects of intake of Eucommia ulmoides leaves on hyperlipidemia, we performed gene expression profiling on rat liver by microarray analysis.Microarray analysis revealed that Eucommia ulmoides leaves up-regulated the gene expression involved in alpha-, beta-, and omega-oxidation of fatty acids, mainly relating to peroxisome proliferator-activated receptor signaling pathway.Overall design: Rats were fed a high-fat diet and high-fructose water without/with orally administration of Eucommia ulmoides leaves for 5 weeks. Livers were taken for RNA extraction and hybridization on Agilent microarrays.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Laboratory of Aquatic Resource Utilization, Department of Marine Biosciences, Tokyo University of Marine Science and Technology
Literatures
- PMID: 21815167
Release date: 2011-08-22
Last updated: 2010-09-27