Protease activated receptor 2 (PAR2) on HEK293 activated by trypsin or 2f-LIGRLO-NH2
Source: NCBI BioProject (ID PRJNA132745)
Source: NCBI BioProject (ID PRJNA132745)
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Project name: Homo sapiens
Description: Human embryonic kidney cell (HEK293) were treated with PAR2 peptide agonist 2f-LIGRLO-NH2 (1.5h, 3h, 6h and 12h) or trypsin (6h). Comparison of genes similarly regulated by both treatments allowed better characterization of PAR2 induced response as both agonists had been reported as non-specific for PAR2.Overall design: Six conditioned experiments with 3 replicates each. Individual grown and harvested.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Medical
Organization: Expression Genomics Lab, Genomics and Bioinformatics, Institute for Molecular Bioscience, Uni of Qld
Literatures
- PMID: 21072196
Release date: 2010-11-19
Last updated: 2010-09-23