Mx-Cre mediated deletion of SRF in murine hematopoietic LSK (Lin-Sca1+c-Kit+) cells
Source: NCBI BioProject (ID PRJNA131803)
Source: NCBI BioProject (ID PRJNA131803)
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Project name: Mus musculus
Description: Analysis of hematopoietic LSK(Lin-Sca1+c-Kit+) cells lacking the Serum response factor (SRF) gene. Results provide insight into the role of SRF in regulating genetic programs important for hematopoietic stem cell developmentOverall design: Comparison of the gene expression profile between murine Lin-Sca1+c-Kit+ cells from Mx-Cre C57BL/6 Srf WT (3) and C57BL/6 Srf KO (3). Cells were sorted by flow cytometry and RNA was harvested and hybridized to Affymetrix MOE430A.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Institut Gustave Roussy, INSERM U985
Literatures
- PMID: 20709909
Release date: 2010-08-12
Last updated: 2010-08-10