Project name: Rattus norvegicus

Description: Rcho-1 trophoblast stem cells can be maintained in a trophoblast stem cell state or induced to differentiate into trophoblast giant cells. During the differentiation process the PI3K pathway is constitutively activated.Microarray analysis of stem, differentiated and differentiated Rcho-1 trophoblast stem cells treated with the PI3K inhibitor LY294002.Overall design: We used gene profiling to determine changes in gene expression between stem and differentiated Rcho-1 trophoblast stem cells. We also identified genes regulated by PI3K in Rcho-1 trophoblast stem cells.

Data type: Transcriptome or Gene expression

Sample scope: Multiisolate

Relevance: ModelOrganism

Release date: 2010-09-15

Last updated: 2010-05-20