Effect of BMP4 and noggin on gene expression in murine R1 ES cells
Source: NCBI BioProject (ID PRJNA125141)

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Project name: Mus musculus
Description: To confirm that the SMAD1/5- and SMAD4-associated genes are direct transcriptional regulators in mESCs in response to BMP, we treated undifferentiated R1 ES cells with BMP4 or with the BMP4 antagonist noggin, which can inhibit BMP signaling effectively for 4 h.Overall design: Undifferentiated R1 ES cells were treated for 4 h with BMP4 or with the BMP4 antagonist noggin, which can inhibit BMP signaling effectively. Untreated R1 ES cells served as the control.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Laboratory of Jing-Dong Jackie Han, Center for Molecular Systems Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
Literatures
  1. PMID: 19926752
Release date: 2010-03-01
Last updated: 2010-02-25