Gene Expression in Gold Nanoparticle Oligonucleotide Complexes treated Primary Immune Cells
Source: NCBI BioProject (ID PRJNA124939)
Source: NCBI BioProject (ID PRJNA124939)
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Project name: Homo sapiens
Description: A transcriptome-wide functional analysis of gene expression implicated multiple signaling pathways specific for Au-NP oligonucleotide complexes.Exposure to Au-NP oligonucleotide complexes is also accompanied by marked activation of immune cells.Overall design: We investigated the effect of Au-NP antisense EGFP oligonucleotide complexes on the transcriptome by expression profiling of 293T cells under four conditions and PBMCs under six conditions with the Affymetrix U133 Plus 2.0 microarray
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Medical
Organization: Feinberg School of Medicine, Northwestern University
Literatures
- PMID: 21697957
Release date: 2010-03-09
Last updated: 2010-03-08