Temporal Gene Expression Profiling of Bone Repair in a Rat Calvarial Defect
Source: NCBI BioProject (ID PRJNA124485)
Source: NCBI BioProject (ID PRJNA124485)
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Project name: Rattus norvegicus
Description: Microarray analysis of gene expression was performed in the healing and non-healing calvarial defects of 12-week old male rats during various stages of bone repair: 1, 3, 5, 7, 10, 14, and 21 days post surgery.Overall design: Eight (CSD) or four (non-CSD) mm circular defects were created in the calvaria. The disc was removed, leaving the underlying dura mater intact. At the respective time post-injury, the region of regeneration was harvested, and RNA isolated using Tri Reagent. Next, labeling and hybridization to Agilent rat whole genome microarrays was performed.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Molecular Pathology, Walter Reed Army Institute of Research
Release date: 2010-03-25
Last updated: 2010-03-19