Project name: Homo sapiens

Description: We recently identified a subset of down-regulated miRNAs such as miR-145 and miR-133a in squamous cell carcinoma. Cell growth inhibitions occurred in miR-145 and miR-133a transfectants compared with the controls, suggesting that both miRNAs function as tumor suppressors. The aims of our expression studies were identification of these miRNAs target genes.Overall design: miR-145 transfected cancer cells vs control cells, miR-133a transfected cancer cells vs control cells

Data type: Transcriptome or Gene expression

Sample scope: Multiisolate

Relevance: Medical

Release date: 2010-01-26

Last updated: 2010-01-25