MeDIP and ChIP-on-chip data from normal Prostate epithelial cells (PrEC) and the LNCaP cancer cell line
Source: NCBI BioProject (ID PRJNA123969)
Source: NCBI BioProject (ID PRJNA123969)
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Project name: Homo sapiens
Description: To identify genomic regions which display concordant epigenetics alterations in prostate cancer, we performed MeDIP and ChIP-on-chip profiling of normal prostate epithelial cells (PrEC) and the prostate cancer cell line LNCaP.These promoter arrays were integrated with expression arrays of the same cells to discover and characterise regions of Long Range Epigenetic Silencing (LRES) in prostate cancer.Overall design: MeDIP and ChIP samples against active and repressive histone marks amplified and hybridised to Affymetrix Human Promoter 1.0R arrays, normalised to Input samples hybridised alongside
Data type: Epigenomics
Sample scope: Multiisolate
Relevance: Medical
Organization: Epigenetics Research Laboratory, Cancer Department, Garvan Institute of Medical Research
Literatures
- PMID: 20173741
Last updated: 2009-12-22