Project name: Schizosaccharomyces pombe

Description: Analysis of histone acetyl transferases (HATs) from the MYST and GNAT families in S. pombe to identify functional differences or overlap with regard to gene expression. Mutations were made to Elp3 and Gcn5 (GNAT family), and to Mst2 (MYST family). Mutants showed distinct phenotypes which were repressed or enhanced by mutant combinations.Overall design: Mutations were made to Gcn5 (GNAT family), and to Mst2 (MYST family) in S. pombe. A treatment of 1M KCl was applied for 60min to some samples. RNA was extracted from the various mutants and hybridized on Eurogentec arrays.

Data type: Transcriptome or Gene expression

Sample scope: Multiisolate

Relevance: ModelOrganism

Release date: 2009-09-20

Last updated: 2009-07-22