Genome-Wide Microarray Analysis of Histone H2B Ubiquitylation mutant strains of Tetrahymena thermophila
Source: NCBI BioProject (ID PRJNA121657)
Source: NCBI BioProject (ID PRJNA121657)
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Project name: Tetrahymena thermophila
Description: Microarray analyses were performed to compare the gene expression profiles of wild-type and several mutant strains of the ciliated protozoan Tetrahymena thermophila. Elimination of H3K4 methylation (hht2-K4Q) and knockout of either of the ubiquitylation enzymes (delta-UBC2 and delta-BRE1) affects a broader spectrum of genes than elimination of H2B ubiquitylation (htb1-K115R).Overall design: Cells at mid-logarithmic growing phase (cell density of 200,000 cells/ml) were collected. Then total RNAs were extracted and hybridized.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Environmental
Organization: Department of Biology, University of Rochester
Literatures
- PMID: 19822522
Release date: 2009-10-27
Last updated: 2009-10-26