Effects of the Fnr homologue AadR on global gene expression
Source: NCBI BioProject (ID PRJNA120515)
Source: NCBI BioProject (ID PRJNA120515)
0 0
Project name: Rhodopseudomonas palustris
Description: In order to define the AadR regulon we did transcriptome analysis of an aadR in frame-deletion mutant and compared to that of wild type. We found that AadR positively modulated expression of 43 genes, most of which are involved in degradation of aromatic acids under anaerobic conditions. It also activated expression of four genes encoding for unknown proteins and a possible DNA-binding stress protein. Furthermore, AadR repressed the expression of 100 genes, including fixK and many genes controlled by FixK, mainly those involved in a microaerobic lifestyleOverall design: R. palustris strains were grown in defined medium anaerobically in light (photosynthetically) in sealed tubes with nitrogen gas in the headspace. Succinate and p-coumarate were provided as carbon sources.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Industrial
Organization: Harwood, Department of Microbiology, University of Washington
Literatures
- PMID: 20487293
Release date: 2010-12-13
Last updated: 2009-11-18