Gene expression in neurons or astrocytes treated with grape seed extract
Source: NCBI BioProject (ID PRJNA116515)
Source: NCBI BioProject (ID PRJNA116515)
0 0
Project name: Rattus norvegicus
Description: We examined the effect of grape seed extract (GSE), which are known to protect neurons against oxidative stress, on primary cultures of hippocampal astrocytes. GSE increased interleukin-6 (IL-6) expression.Microarrays are used to examine the effects of GSE on primary cultures of hippocampal neurons and astrocytes.Overall design: Primary cultures of hippocampal neurons were treated with 0, 1, or 10 ug/ml of GSE for 24 hrs. Primary cultures of hippocampal astrocytes were treated with 0, 1, 10, or 100 ug/ml of GSE for 24 hrs.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Division of Safety Information on Drug, Food and Chemicals, National Institute of Health Sciences
Literatures
- PMID: 19381798
Release date: 2009-04-09
Last updated: 2009-03-18