Profiling of novel p53-inducing compounds
Source: NCBI BioProject (ID PRJNA112735)
Source: NCBI BioProject (ID PRJNA112735)
0 0
Project name: Homo sapiens
Description: We describe six novel lead compounds activating the p53 tumor suppressor pathway. Transcriptional profiling indicated that they invoked highly similar responses involving p53 and cell cycle pathways and DNA damage response signaling.Keywords: Stress responseOverall design: Six compounds and one vehicle control, with four biological replicates each, for a total of 28 samples.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Medical
Organization: MRS, Radiation Oncology, Johns Hopkins University
Release date: 2010-10-01
Last updated: 2008-09-04