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PRJNA112557
Early-induced genes of human regulatory CD4+CD25hi Treg and CD4+CD25- Th cells
Source: NCBI BioProject (ID PRJNA112557)

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Project name: Homo sapiens
Description: Goals and objectives of this study: to identify genes preferentially induced in human CD4+CD25hi Treg cells following T-cell activation with potential role for stabililization & maintenance of the regulatory program.Keywords: T-cell receptor stimulation, gene-regulation, comparative gene expression profilingOverall design: Homo sapiens CD4+CD25- and CD4+CD25hi T cells were sorted from healthy individual donors and analyzed ex vivo (non-activated) or 1 day following T-cell receptor activation using anti-CD3/IL2 and anti-CD3/-CD28/IL2 (activated), respectively.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Medical
Organization: Genome Analytics, Dep. Molecular Bacteriology, HCI - Helmholtz Centre for Infection Research
Literatures
  1. PMID: 19453521
Release date: 2009-04-20
Last updated: 2008-10-02