p53- repressed miRNAs are involved with E2F in a feed forward loop promoting proliferation
Source: NCBI BioProject (ID PRJNA111127)
Source: NCBI BioProject (ID PRJNA111127)
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Project name: Homo sapiens
Description: There is a distinctive miRNA expression profile between early (young) and replicative senescence (old).We observed a cluster of miRNAs that were repressed upon senescence in both MRC-5 and WI-38 fibroblast cells.Overall design: miRNAs profiling in young and senescence human emryonic fibroblasts (MRC-5 and WI-38)
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Medical
Organization: Labratory of Human Carcinogenesis, CCR, NCI
Literatures
- PMID: 19034270
Release date: 2008-09-25
Last updated: 2008-09-17