Rat lung gene expression during acute pulmonary embolism
Source: NCBI BioProject (ID PRJNA110709)

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Project name: Rattus norvegicus
Description: Rats were given pulmonary embolism by i.v. injection of 25 micron polystyrene microspheres or 0.01% Tween20 solution as vehicle controlEmbolism of microspheres is irreversible and causes dose dependent pulmonary hypertensionKeywords: time course and dose responseOverall design: Rats received one of three treatments: 0.15 ml/100 grams weight of 0.01% Tween20 as "vehicle" control; 0.10 ml/100 grams of 10% microsphere suspension in 0.01% Tween20 = 1.3 million/100 grams = "PE1.3" dose; 0.15 ml/100 grams of 10% microspheres = 2.0 million/100 grams = "PE2.0" dose; rats were euthanized at either 2 hours or 18 hours after treatment
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Cannon Research Center, Emergency Medicine, Carolinas Medical Center
Literatures
  1. PMID: 27435598
Release date: 2009-09-01
Last updated: 2008-11-08