Identification of spondylarthropathy-specific genes in BALB/c mice with proteoglycan-induced spondylitis (PGIS)
Source: NCBI BioProject (ID PRJNA110611)
Source: NCBI BioProject (ID PRJNA110611)
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Project name: Mus musculus
Description: BALB/c mice develop peripheral arthritis (PGIA) and spondyloarthropathy (PGIS) upon repeated intraperitoneal injections of human cartilage proteoglycan (PG) aggrecan. The aim of the present study was to identify spondylitis-specific genes by comparing intervertebral disc (IVD) RNA samples from spondyloarthropathic and naïve BALB/c mice.Keywords: Genetic modificationOverall design: We compared the gene expression data of 5 spondyloarthropathic and 3 naïve (control) mice.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Molecular Medicine, Orthopedic Surgery, Rush University Medical Center
Last updated: 2008-12-01