Effect of an AhR-/- on transcription in CD4 T cells from the spleen.
Source: NCBI BioProject (ID PRJNA108651)

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Project name: Mus musculus
Description: CD4+ T cells from 8-12 week female mice were isolated from wt and AhR-/- mice 24h after injection of 10µg/kg TCDD or solvent control.Keywords: TCDD, AHR, immunosuppressionOverall design: Each experiment was performed in biological duplicates from 4 pooled animals. Since TCDD treatment showed only marginal impact on the gene expression (~10 transcripts effected in wt mice) wt - ko comparisons were performed on pooled profiles from TCDD and solvent mice.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Immunology, Institute for Environmental Research
Literatures
  1. PMID: 16972790
Release date: 2008-11-25
Last updated: 2008-01-07