Project name: Mus musculus

Description: To find genes deregulated in the pathogenisis of T-cells in Atm deficient mice, we performed expression profiling of Atm deficient thymic lymphomas, wildtype thymi and Atm deficient thymi without macroscopic enlargement, representing an intermediate stage in the process of tumorigenisis.Keywords: genetic modification, disease state analysisOverall design: To evaluate differential gene expression of Atm deficient thymic lymphoma we performed microarray based expression profiling of 8 Atm deficient thymic lymphomas, 6 wildtype thymi, 1 thymus of an Atm heterozygous mouse and 18 thymi of Atm deficient mice without macroscopic enlargement.

Data type: Transcriptome or Gene expression

Sample scope: Multiisolate

Relevance: ModelOrganism

Release date: 2008-07-15

Last updated: 2008-03-13