Integrin alpha6-beta4 control the expression of genes associated with cell motility, invasion and metastasis
Source: NCBI BioProject (ID PRJNA106385)

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Project name: Homo sapiens
Description: The objective of this study was to determine the gene expression changes mediated by the alpha6beta4 integrin using MDA-MB-435 breast carcinoma cell line under normal culturing conditions (10% FCS in DMEM).Keywords: Transfection (stable)Overall design: Comparison of clones of MDA-MB-435 cells transfected with the integrin beta4 subunit (which results in cell surface expression of the integrin apha6beta4 integrin; clones 3A7 and 5B3) to those transfected with vector (mock; 6D2 and 6D7) only.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Medical
Organization: Surgery, University of Texas Medical Branch
Literatures
  1. PMID: 19011242
Release date: 2008-12-01
Last updated: 2008-05-15