An E2F1-Dependent Gene Expression Program That Determines the Balance Between Proliferation and Cell Death
Source: NCBI BioProject (ID PRJNA103283)
Source: NCBI BioProject (ID PRJNA103283)
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Project name: Rattus norvegicus
Description: E2F1 has been shown to induce both proliferation and apoptosis.We now show that PI3K/Akt signaling regulates the balance of these events by specifically blocking expression of genes in the E2F1 apoptotic program but not the proliferative program.Keywords: PI3K dependent modulation of E2F1 gene expression measured by Affymetrix gene expression analysisOverall design: 11 samples total, two replicates each (except Sample 1 which is represented once)
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Pediatrics, University of Minnesota
Literatures
- PMID: 18167336
Release date: 2007-11-02
Last updated: 2007-11-01