Description: Our findings establish GATM as a multifunctional regulator of spermatogenesis, integrating creatine-dependent energy metabolism with translational capacity, organelle architecture, and immune-related gene regulation. The coordinated disruption of mitochondrial and ribosomal pathways provides a novel mechanistic framework for understanding the metabolic origins of male infertility.

Data type: Transcriptome or Gene expression

Sample scope: Monoisolate

Relevance: Model organism

Release date: 2026-03-11

Last updated: 2026-03-11

Data size: 47.53GB