PPAR Subtypes Determine Distinct Modes of Action of PAEs and PFAS in Disrupting Human Macrophage Alternative Activation
Source: CNGBdb Project (ID CNP0008236)
Source: CNGBdb Project (ID CNP0008236)
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Description: Human THP 1 cells were respectively knocked out of PPARa, d and g using CRISPER CAS9 technology. After being induced into substitution-activated macrophages by PMA, IL 4 and IL 13, they were compared with wild type macrophages. Meanwhile, wild-type cells were treated with 100 uM concentrations of PFOS.
Data type: Transcriptome or Gene expression
Sample scope: Monoisolate
Relevance: Environmental
Submitter: 庄志森(Zhuang zhisen); 南方医科大学
Release date: 2025-10-31
Last updated: 2025-10-31
DOI: 10.26036/CNP0008236
Data size: 18.84GB