Description: Multiple sclerosis (MS) is initiated by peripheral autoreactive T cells that infiltrate the central nervous system (CNS) and mediate demyelination. Although tolerogenic dendritic cell (tolDC) vaccines show promise for restoring antigen-specific immune tolerance, their clinical application is hindered by poor migration, limited antigen presentation, and instability in inflammatory conditions. Here, we developed a 3D-printed tolerogenic artificial lymph node (tol-aLN) to overcome these limitations.

Data type: Raw sequence reads; Transcriptome or Gene expression

Sample scope: Monoisolate

Release date: 2025-07-15

Last updated: 2025-07-15

Data size: 267.51GB