Description: This study investigates the impact of prolonged areca nut chewing on the oral microbiome using a strain-resolved approach. Saliva samples from 80 long-lived elderly individuals, all aged over 80 years, were analyzed through shotgun metagenomics to explore the effects of this habitual behavior on microbial composition and functional dynamics. By combining species and functional profiling with strain-level genomic analysis, the study aims to uncover how areca nut chewing influences microbial communities and metabolic pathways. This comprehensive approach provides a deeper understanding of the interactions between lifestyle factors and oral microbiota, offering novel insights into the potential microbial mechanisms underlying health risks associated with areca nut use.

Data type: Raw sequence reads

Sample scope: Multispecies

Relevance: Medical

Release date: 2025-02-19

Last updated: 2025-02-19

Data size: 406.41GB