Description: Much less is known about the PM localized RNA and its function in cellular homeostasis and diseases. Here, using a PM located APEX mediated proximity labeling strategy followed by RNA sequencing, we uncover the existence of RNAs in the PM of cardiomyocytes. Among them, the most abundant lncRNA in PM fractions is identified to be interacted with b1AR and promotes isoproterenol induced cAMP signaling activation.

Data type: Genome sequencing and assembly; Raw sequence reads; Genome sequencing; Assembly

Sample scope: Monoisolate

Release date: 2024-01-10

Last updated: 2024-01-10

Data size: 96.48GB