Description: Lymph node metastasis of solid tumors is a common phenomenon, and it is one of the harbingers and pathways of distant organ metastasis, which often leads to poor prognosis of patients. The esophagus has a special structure and is surrounded by a dense lymphatic network. Compared with other cancers, lymph node metastasis of esophageal cancer is more common and is the main way of distant metastasis. More than 80% of distant organ metastasis occurs through lymph nodes. The metastasis of lymph nodes and the number of positive lymph nodes are important clinical indications, which will affect the choice of treatment options and prognosis. However, there is no systematic microscopic study on the mechanism of lymph node metastasis in esophageal cancer. Study the mechanism of proximal metastasis of esophageal cancer, compare the immune microenvironment and cancer cell characteristics of patients with and without metastasis, and patients with different treatment responses, explore the subclonal selection of tumors, and search for prognostic-related molecules, etc., for auxiliary tumor diagnosis and treatment Guidance matters.

Data type: Raw sequence reads; Epigenomics; Transcriptome or Gene expression

Sample scope: Multiisolate

Relevance: Medical

Release date: 2025-06-29

Last updated: 2025-06-29

Data size: 14.47TB