Description: Lower respiratory tract infections are common in children. Bronchoalveolar lavage fluid has long been established as the best biological sample to detect infection; however, it is not easily collected in children. Sputum may be used as an alternative yet its diagnostic accuracy remains controversial. Therefore, this study sought to evaluate the diagnostic accuracy of sputum for detecting lower respiratory tract infections using metagenomic next-generation sequencing. Paired sputum and bronchoalveolar lavage fluid samples were obtained from 68 patients; pathogens were detected in 67 and 64 sputum and bronchoalveolar lavage fluid samples by metagenomic next-generation sequencing, respectively.

Data type: Metagenome

Sample scope: Multiisolate

Relevance: Medical

Release date: 2023-08-16

Last updated: 2023-07-07

Data size: 27.93GB